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*Schools currently available: Cummings School of Veterinary Medicine, School of Dental Medicine, School of Engineering, The Fletcher School of Law and Diplomacy, Friedman School of Nutrition Science and Policy, School of Medicine, and Graduate School of Biomedical Sciences.

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Highly Stereoselective Glycosylation Reactions

Technology
Researchers at Tufts University have developed a new method to generate 1,2-cis-a-glycosides without the need for specialized directing groups. The new synthetic approach uses thioglycoside donors
https://viceprovost.tufts.edu/highly-stereoselective-glycosylation-reactions

Digital to Analog Converter Circuit

Technology
A Digital-to-Analog Converter based on Resistive Interpolation Load Prof. Sameer Sonkusale at the Electrical and Computer Engineering Department at Tufts has developed a single chip integrated DAC
https://viceprovost.tufts.edu/digital-analog-converter-circuit

Cyclic Peptide Structure Prediction via Structural Ensembles Achieved by Molecular Dynamics and Machine Learning (StrEAMM)

Technology
­Efficient Development of Orally-Bioavailable Cyclic-Peptide Drugs via Molecular Dynamics + Machine Learning BACKGROUND Cyclic peptides are a promising drug modality, combining beneficial traits from
https://viceprovost.tufts.edu/cyclic-peptide-structure-prediction-structural-ensembles-achieved-molecular-dynamics-and-machine

New Neisseria gonorrhoeae Vaccine Antigens Expressed During Natural Mucosal Infection

Technology
SUMMARY Researchers at Tufts University discovered novel antigens for a gonococcal vaccine through a unique candidate antigen selection strategy. In vivo, these previously unconsidered protein
https://viceprovost.tufts.edu/new-neisseria-gonorrhoeae-vaccine-antigens-expressed-during-natural-mucosal-infection

Novel IL-38 Analogues are Potent Inhibitors of Neuroinflammatory Mediators

Technology
SUMMARY A Tufts University investigator and their collaborators at R&D Systems Inc., have developed novel IL-38 analogues to treat neuroinflammatory and neurodegenerative diseases like Autism Spectrum
https://viceprovost.tufts.edu/novel-il-38-analogues-are-potent-inhibitors-neuroinflammatory-mediators

Novel Non-Flushing Niacin Derivatives and Mimetics

Technology
SUMMARY A researcher from the Tufts University School of Medicine has developed novel derivatives of Niacin, which do not produce the uncomfortable side effect of flushing and reddening of the skin
https://viceprovost.tufts.edu/novel-non-flushing-niacin-derivatives-and-mimetics

Are Americans Eating Enough Whole Grains? It Depends on Who You Ask

Research Brief

There are multiple competing definitions of a whole-grain food—a new study points to need to build a consensus

https://viceprovost.tufts.edu/research-briefs/are-americans-eating-enough-whole-grains-it-depends-who-you-ask

Potential Treatment Target for Drug-Resistant Epilepsy Identified

Research Brief

A new study by Tufts researchers found a molecule that could be a target for treatment in patients who have become resistant to traditional anti-seizure drugs

https://viceprovost.tufts.edu/research-briefs/potential-treatment-target-drug-resistant-epilepsy-identified

Potential Treatment Target for Rare Form of Infant Epilepsy Identified

Research Brief

Research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences lends hope to families of patients with infantile spasms syndrome

https://viceprovost.tufts.edu/research-briefs/potential-treatment-target-rare-form-infant-epilepsy-identified

Study: Lipids Can Cause Organelle Miscommunication in Neurodegenerative Disease

Research Brief

Tufts School of Medicine researchers find protein mutations associated with brain disorders cause different kinds of molecules to build up where mitochondria and endoplasmic reticulum connect and share information

https://viceprovost.tufts.edu/research-briefs/study-lipids-can-cause-organelle-miscommunication-neurodegenerative-disease