A novel quantitative hemodynamic model relating physiological perturbations in cerebral blood volume, blood flow, and oxygen consumption to the associated hemodynamic effects that are measurable with

The difficulties encountered in the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in the subsurface have spawned numerous studies relating to evaluation of the benefits of DNAPL

Summary: The invention is a structural composite tube that is initially flexible and will be folded up to reduce its storage space requirements. The composite tube will then be inflated with a gas to

SUMMARYPeriodontitis is a common disease of the oral cavity that affects over 47% of individuals in the US that are over 30 years old and over 70% of adults over 65. Recent studies have shown the

TestLicensing ContactChiara VannucciChiara.Vannucci@tufts.edu

SUMMARY Researchers at Tufts University discovered novel antigens for a gonococcal vaccine through a unique candidate antigen selection strategy. In vivo, these previously unconsidered protein

A series of stimulus-responsive protein modifications to enhance intracellular protein drug delivery.Download a .pdf version of this invention hereIntellectual PropertyUS Publication 2016

SUMMARY Tufts University investigator Nikhil Nair and his team have developed a novel directed evolution workflow to rapidly engineer ammonia lyase (AL) class enzymes for large sequences that are

Inhibitors of Clostridium difficile spore germinationTufts case T001523Technology• Spore formation by Clostridium difficile is a significant obstacle to overcoming hospital-acquired C. difficile

Why is the target important?The PI3 lipid kinase (PI3K) pathway is an important target for anti-cancer drug development because:It’s activated by growth factors, oncogenes (RAS), GPCRs, etc. It