Institutional Animal Care & Use Committee

The Institutional Animal Care & Use Committee (IACUC) ensures institutional compliance with federal regulations that govern animal care and use for all research, teaching, and training projects.

IACUC Personnel Requirements

Personnel requirements must be completed before work with animals can begin. Once the requirements have been met, personnel may be added to an approved IACUC protocol and will receive IACUC Clearance to begin animal work. See more information about these requirements in the following sections.

Personnel that have completed their requirements can be added to an approved IACUC protocol by submitting a Personnel Amendment (Supplement P). If you are currently waiting on IACUC approval of a new protocol, please be sure that personnel who will work on the protocol are using this preparatory time to complete all requirements.

CLICK HERE to access the materials necessary for these requirements (OHS Forms, MACU, and RSS trainings). If you need the password or any other information regarding personnel requirements, contact the IACUC Office.

IACUC Clearance

IACUC Clearance must be attained prior to personnel beginning any animal work. Personnel and their Principal Investigators will receive a notification once their requirements are complete and they have attained IACUC clearance. Clearance is granted only after the following requirements have been completed:

  • Completion of the Occupational Health and Safety (OHS) assessment
  • Completion of the relevant IACUC trainings:
    • Mandatory Animal Care and Use (MACU) Training
    • Rodent Survival Surgical (RSS) Training, if applicable

Please review the IACUC Policy on Requirements for Personnel Working with IACUC-Covered Animals for more information about requirements.

Occupational Health and Safety (OHS) Assessment

Federal regulations require an occupational health and safety (OHS) program to be a part of the overall animal care and use program in order to maintain a safe and healthy workplace. Protocol personnel are required to have an annual OHS assessment, regardless of their level of interaction with animals and whether anything has changed since their last assessment. Once the OHS Assessment has been reviewed, the OHS staff will send a notification to the IACUC office regarding your status.

Please note that only the OHS staff may review health information, therefore please direct any questions, concerns or medical forms directly to the OHS staff for your campus. Any medical forms sent to the IACUC office will be deleted without review.

Mandatory Animal Care and Use (MACU) Training

The IACUC provides a standardized training of institutional and regulatory requirements called the Mandatory Animal Care and Use (MACU) training. It provides education on how to comply with animal regulations and institutional policies and requirements. Protocol personnel are required to complete this training prior to working with live animals and must repeat the training every three years. In the interim, it can serve as a useful resource for many questions concerning the IACUC and review of animal research.

To receive credit, you must view the presentation, review the institutional policies, and complete and pass the quiz.

Rodent Survival Surgery (RSS) Training

Personnel that will conduct survival surgery on rodents must complete the RSS training as a part of their IACUC clearance and repeat the training every three years. This must be done prior to conducting survival surgery. The IACUC office must be notified of intent to conduct survival surgery by indicating on the Supplement P form or by email if the person is already listed on the protocol. The IACUC office will then contact the personnel with the training instructions.

Tufts CMS, LAMS, and CBU offer additional training on rodent handling and surgical techniques. Please reach out to those groups for more information.

Access Requests

After IACUC clearance has been attained, information about getting an ID and/or access to the animal facilities can be requested by emailing:


Annual completion of the OHS assessment is required. Both MACU and RSS training must be repeated every 3 years. The IACUC office will begin sending renewal reminders well in advance of the expiration date. If an individual fails to renew OHS or mandatory training requirements, the IACUC office will remove the person from the animal protocol, revoke animal facility access, and inform the Principal Investigator that the person is not approved to work with animals.

Addition of personnel to an active protocol can be done administratively through the use of a Supplement P. Email the completed form to the IACUC-office@tufts.edu. Click here for more information on personnel amendments.

The IACUC office cannot legally receive or transmit any OHS forms. Only the OHS staff may review health information. Please direct any questions, concerns, or medical forms directly to the OHS staff for your campus which can be found on the Materials webpage.

Absolutely! Please email IACUC-office@tufts.edu for more information on personnel requirements and instructions for accessing the Materials webpage. Principal Investigators are to share this information with any personnel who will be working on their IACUC protocols, prior to IACUC approval.

After you complete both the MACU and OHS assessment, you will receive an IACUC clearance notification. Once you receive this notification, you will be added to the appropriate IACUC protocol and are free to request access by emailing IACUC-office@tufts.edu.

The animal health services group on each campus (Tufts CMS, LAMS, and CBU) offers supplemental trainings on technical procedures. Please reach out to them directly for additional training.