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Why is the target important?The PI3 lipid kinase (PI3K) pathway is an important target for anti-cancer drug development because:It’s activated by growth factors, oncogenes (RAS), GPCRs, etc. It
https://viceprovost.tufts.edu/novel-small-molecule-inhibitors-phosphatidylinositol-345-trisphosphate-pip3
Aspects of this invention are required for the construction of silk-based optical and electronic devices.Researchers at Tufts University have developed methods to utilize silk fibroin in the
https://viceprovost.tufts.edu/silk-based-ofet-olet-biologically-active-transistors
Flexible Parylene Metamaterials
Technology
BACKGROUND Terahertz radiation is useful for a variety of applications. For example, because of its ability to penetrate most clothing, terahertz radiation provides a way to detect concealed weapons
https://viceprovost.tufts.edu/flexible-parylene-metamaterials
Download a .pdf version of this invention hereResearchers at Tufts University have developed novel methods for fabricating nano- and micro-particles from silk. These biocompatible, biodegradable
https://viceprovost.tufts.edu/preparation-silk-nanospheres-and-microspheres-silkpva-blend-films
Unmet need: Declining petroleum resources have heightened the interest in biomass as potentially the only sustainable source of organic carbon that can be used in the chemical and energy industry
https://viceprovost.tufts.edu/conversion-biomass-gaseous-fuel-hydrocarbons
Silk based hydrogels made through electrogelation (e-gels) are excellent biocompatible adhesives. Once formed, these e-gels can be reversible which makes them excellent candidates for on-demand
https://viceprovost.tufts.edu/electrogelation-silk-and-devices-silk-electrogelation-and-delivery
BACKGROUND Silver catalysts can be used for ethylene epoxidation and appear promising for selective catalytic reduction (SCR) of NOx with hydrocarbons. For example, silver catalysts have potential
https://viceprovost.tufts.edu/so2-stabilization-dispersed-silver-alumina-high-temperatures
BACKGROUND Between the optical frequencies and the microwave frequencies is a broad expanse of spectrum in the terahertz range. However, development of devices for operation in the terahertz range is
https://viceprovost.tufts.edu/metamaterial-phemt-hybrid-devices-terahertz-sources-modulators-and-detectors
Researchers at Tufts University have developed novel silk biomaterials that are surface-modified with polyethylene glycol (PEG). These materials have utility in various biomedical applications where
https://viceprovost.tufts.edu/surface-modification-silk-fibroin-peg-use-anti-adhesion-barriers-and-anti-thrombotic-materials
Inhibitors of Clostridium difficile spore germinationTufts case T001523Technology• Spore formation by Clostridium difficile is a significant obstacle to overcoming hospital-acquired C. difficile
https://viceprovost.tufts.edu/inhibitors-clostridium-difficile-spore-germination-and-outgrowth