Below is a digest of exciting articles and announcements concerning COVID-19 research and clinical advances recently in the news. Please return for weekly updates.

• Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
  • This article highlights how the immune system may not be responding to SARS-CoV-2 in a manner that prevents viral replication, thus leading to more complicated and severe illnesses.
• Cross-neutralization of SARS-CoV-2 by a Human Monoclonal SARS-CoV Antibody
  • The authors discuss how a human antibody of SARS-CoV effectively neutralizes SARS-CoV-2 and could potentially be used as a therapeutic for high-risk individuals and as a post-exposure treatment to reduce the effects of COVID-19.
• Immune Response to SARS-CoV-2 and Mechanisms of Immunopathological Changes in COVID-19
  • The review provides a detailed look at the different immunological impacts of SARS-CoV-2 on the human immune system.
• Subjective Neurological Symptoms Frequently Occur in Patients With SARS-CoV2 Infection
  • The authors discuss how SARS-CoV-2 impacts the central nervous system, and that this has created the need for more research into what the virus does to the CNS and what complications this could cause.
• Liver injury is associated with severe Coronavirus disease 2019 (COVID‐19) infection: a systematic review and meta‐analysis of retrospective studies
  • Using different databases, the authors of this article performed meta-analysis of retrospective studies regarding COVID-19 and hoped to find a link between more severe infection and liver damage.
• Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19
  • The authors explore symptoms other than the typical respiratory response that could be linked to COVID-19 infection of the liver, pancreas, and GI tract.
• COVID-19 and diabetes mellitus: An unholy interaction of two pandemics.
  • The authors highlight the interactions that occur between COVID-19 and diabetes, and how the two create a vicious cycle of each worsening the other.
• SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate.
  • The authors review a specific mutation of SARS-CoV-2 and identify it as being linked to more severe cases of COVID-19, hoping to use this data to influence vaccine development.