The Osterweil lab is recruiting a motivated individual to fill a postdoctoral position in molecular neuroscience. You will be joining the exciting, fast-paced environment at Boston Children’s Hospital/ Harvard Medical School investigating cell type-specific mRNA translation in neural function and dysfunction (www.osterlab.org/).

Our group has a number of hypothesis-driven projects that are aimed at identifying critical mechanisms in neural plasticity, and determining how these processes go awry in neurodevelopmental disorders such as fragile X syndrome. We are using molecular approaches including TRAP-seq, scRNA-seq, and spatial transcriptomics, and combining these with electrophysiological and behavioral assays to answer research questions and test potential therapeutic approaches that arise from this work. We are also employing new models to determine the conservation of synaptic mechanisms between mouse and human.

Candidates must have a PhD in neuroscience, cell biology, or a related field, and show evidence of good productivity in the form of publications. Experience with either molecular neuroscience and mouse brain surgical techniques, or RNA-seq and bioinformatics, is greatly preferred.

Please send a CV, cover letter with statement of interest, and 2-3 letters of references to:
emily.osterweil@childrens.harvard.edu. Applications will be accepted until a suitable candidate is found.

Boston Children’s Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability.

Boston Children’s Hospital requires all employees to be vaccinated against COVID-19 and Flu, (unless you are eligible for a medical or religious exemption).

Closing Date: N/A (until appropriate applicant is found)

Are you passionate about inter-disciplinary research in molecular biology and medicine? Want to be a part of National Institute of Health and American Heart Association funded studies at the intersection of cardiology and oncology, disease mechanism and therapy, and join a collaborative and supportive team environment at the heart of Boston, U.S.A.?

A Postdoctoral Research Fellow position (2 years, extendable beyond that) is available in the Molecular Cardiology Research Institute (MCRI), Tufts Medical Center, Chen laboratory. We investigate the impact of autophagy, a cellular degradative and recycling process, on the heart and tumor utilizing state-of-the-art autophagy imaging technology (Nat Biomed Eng. 2022 Sep;6(9):1045-1056). We are passionate about optimizing autophagy modulation as a viable therapeutic strategy that is translatable (PLoS One.2023 Mar 16;18(3):e0282859). Our experimental approaches include: in vitro cell models, molecular biology, high resolution intravital microscopy, flow cytometry, state-of-the-art in vivo molecular imaging of the cardiovascular system and tumor in murine disease models, in vivo cardiovascular function studies, mitochondrial biology and metabolism, multiomics and signaling studies, extracellular vesicles, pharmacology, nanoparticles, nanoprobe synthesis, theranostics. Our long-term goal is to translate the molecular insights gained from the bench to improve cardiovascular and human health.

Candidates will hold a PhD, MD/PhD, or equivalent in biology, bioengineering, or health sciences fields, have excellent writing and communications skills, and committed to a career in cardiovascular science. The postdoc will have the opportunities to submit to fellowship and other grant funding mechanisms to prepare for an independent career. Prior experience in autophagy, apoptosis, cell biology, molecular imaging, small animal experimentation is desirable but not required.

We are an international, diverse, inclusive group. Underrepresented minorities or women are encouraged to apply. Please send cover letter, curriculum vitae, and two to three reference contacts or letters to Howard Chen (Howard.Chen@tuftsmedicine.org), cc Debbie Slater (Debbie.Slater@tuftsmedicine.org).

To find out more about what we work on, check out: https://go.tufts.edu/ChenLab

Closing Date: 06/24/24

The Environmental Health Research Group at Tufts University is currently conducting studies examining the interplay between airborne fine particles, metal exposures and dementia and cognitive function. Our research adopts a multi-disciplinary approach, integrating pathological analyses of brain tissue, identification of particulate matter and metal content, and epidemiological assessments of long-term ambient air pollutant exposures. Through this approach, our aim is to delineate the pathways through which environmental pollutants impact brain health.

We are actively seeking to enhance our research team by adding a postdoctoral fellow specializing in environmental epidemiology.  This position is fully funded for multiple years.  In addition to hands-on research experience, the position provides access to various professional training opportunities, including workshops on grant writing, career workshops, and skill enhancement. 

Successful candidates will demonstrate expertise in epidemiology, biostatistics, and/or exposure science.  Proficiency in statistical programming languages such as R and/or SAS, along with strong analytical skills are essential.  Knowledge or familiarity with neuroscience would be an added bonus.

To apply for this position, please submit your resume or curriculum vitae (CV) to helen.suh@tufts.edu.

Requirements:

• Ph.D. or equivalent in epidemiology, environmental health, or related disciplines at the time of appointment
• Demonstrated expertise in epidemiology, biostatistics, and/or exposure science.  Knowledge or familiarity with neuroscience is a plus.
• Proficiency in statistical programming languages (e.g., R, SAS)

Closing Date: 08/04/24

The Kohlgruber Lab investigates the immune-specific basis of human diseases and applies high-throughput molecular, genetic, and immunological assays to decipher immune system specificities and interactions. We combine human and mouse immunology, with single-cell transcriptomics, synthetic biology, and immune-receptor specificity screening approaches to understand the molecular underpinnings of autoimmunity, cancer, and infectious disease. Our work lies at the intersection of translational immunology and biotechnology, where we seek to pioneer innovative strategies to improve our ability to interrogate and modulate the immune system and leverage our findings toward the development of precision vaccines and immunotherapeutics.

We are seeking a postdoctoral research fellow to work on an exciting research project dissecting the antigen-specific basis of autoimmunity. The research project will utilize human samples and cell lines to study the antigen specificity and function of synovial T cells in rheumatoid arthritis and checkpoint inhibitorinduced autoimmune adverse events. Multidimensional analyses will be used to conduct the research, including flow cytometry, single-cell profiling, genome-wide T cell antigen discovery screens, high throughput T cell repertoire analysis, autoantibody specificity profiling using PhIPseq, spatial transcriptomics, and in vitro functional assays. The research will require that the individual be a keen learner, have excellent communication skills, be comfortable with new technology, and work as a member of a highly collaborative team. The lab works closely with immunologists, rheumatologists, and oncologists to participate in rewarding translational immunology research.

The lab is part of the Division of Immunology at Boston Children’s Hospital. The Boston area is a vibrant and dynamic scientific community that offers unique opportunities for scientific growth and provides many opportunities to interact with other PIs and trainees. The successful candidate will have access to the larger Harvard Medical School environment for training, access to core facilities, and seminars. The Kohlgruber Lab strives to create an impactful and supportive research environment, prioritizes mentorship, and enables people to get to the next step in their careers.

Qualifications:

• Successful candidates must hold (or soon receive) a Ph.D., M.D., or M.D/Ph.D. degree in the field of immunology, molecular and/or cellular biology, genetics, biostatistics/bioinformatics, or other quantitative sciences.
• Candidate(s) should have a strong track record of productivity, or domain expertise, as evidenced by first-authored publications in peer-reviewed scientific journals/preprints or demonstrated contribution to ongoing projects.
• Candidate(s) should have the communication and interpersonal skills required to make a positive contribution to a thriving intellectual environment and work collaboratively in a team.
• Other desired (but not required) skills for this position include experience with human T cell assays, ability to run multi-color flow cytometry, processing and analyzing single-cell transcriptomics datasets, and/or biotechnology development.

Application Information:

• Review of applications will begin immediately and be considered on a rolling basis.
• Full-time position with competitive salary/benefits commensurate with experience. The position is fully funded and may be held for up to 5 years.
• To apply, please email Dr. Ayano Kohlgruber (Ayano.Kohlgruber@childrens.harvard.edu) with the following documents:
  • An updated curriculum vitae (CV).
  • A brief statement or cover letter of research interests, motivation, and experience; or publication/manuscript/pre-print the candidate has written.

Closing Date: 05/31/24

Funding opportunity from the ADCES Foundation and the Certification Board for Diabetes Care and Education (CBDCE), to support the career of emerging leaders in diabetes care and education. The research fellowship reinforces long-term goals by both organizations to build on existing research in diabetes care and enhance health outcomes for people with diabetes, prediabetes and other cardiometabolic conditions.

More information can be found on the ADCES Foundation website.

If you are an early career scientist who is interested in this opportunity, please reach out to the ADCES Research Fellowship Committee at grants@adces.org.

• BPDA Job Openings
• Job Search Engine by the NPDA