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Targeted Prevention for Tickborne Diseases (R01 Clinical Trial Not Allowed) RFA-AI-19-037

The purpose of this Funding Opportunity Announcement (FOA) is to encourage the development of vaccines and other approaches for the prevention of Lyme disease and/or other tick-borne diseases.

This FOA is designed to encourage the research community to develop a range of approaches for preventing TBDs in humans using both established and novel technologies. This FOA will support approaches including, but not limited to:

  • Identifying and testing antigens for human vaccines against tick-borne pathogens
  • Development and evaluation of vaccine candidates (excluding clinical trials)
  • “Anti-tick” vaccines to elicit immune responses against tick salivary proteins or other antigens
  • Reservoir-targeted vaccines to interrupt sylvatic transmission
  • Other reservoir-targeted approaches to interrupt the natural history of infection
  • Transgenic and para-transgenic approaches in ticks or reservoirs to interrupt tick-borne pathogen uptake, colonization, or transmission

Application Due Date: August 6, 2019