The purpose of this Funding Opportunity Announcement (FOA) is to encourage the development of vaccines and other approaches for the prevention of Lyme disease and/or other tick-borne diseases.
This FOA is designed to encourage the research community to develop a range of approaches for preventing TBDs in humans using both established and novel technologies. This FOA will support approaches including, but not limited to:
Identifying and testing antigens for human vaccines against tick-borne pathogens
Development and evaluation of vaccine candidates (excluding clinical trials)
“Anti-tick” vaccines to elicit immune responses against tick salivary proteins or other antigens
Reservoir-targeted vaccines to interrupt sylvatic transmission
Other reservoir-targeted approaches to interrupt the natural history of infection
Transgenic and para-transgenic approaches in ticks or reservoirs to interrupt tick-borne pathogen uptake, colonization, or transmission