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Personnel can be added to an IACUC protocol at any time after the protocol is approved by submitting a Personnel Amendment. If you are currently waiting on IACUC approval of a new protocol, please be sure that personnel who will work on the protocol are using this preparatory time to complete all requirements. Instructions for accessing the Materials webpage are provided on all IACUC protocol forms and Personnel Amendment forms. For specific personnel information, you can contact

IACUC Clearance

IACUC Clearance must be attained prior to personnel beginning any animal work. Personnel and their investigators will receive a notification once their requirements are complete and they have attained IACUC clearance. Clearance is granted only after the following requirements have been completed:

  • Addition to the relevant protocol via the Supplement P form
  • Completion of the Occupational Health and Safety (OHS) assessment
  • Completion of the relevant IACUC trainings:
    • Mandatory Animal Care and Use (MACU) Training
    • Rodent Survival Surgical (RSS) Training, if applicable

Please review the IACUC Policy on Requirements for Personnel Working with IACUC-Covered Animals for more information about requirements.

Occupational Health and Safety (OHS) Assessment

Federal regulations require an occupational health and safety (OHS) program to be a part of the overall animal care and use program in order to maintain a safe and healthy workplace. Protocol personnel are required to have an annual OHS assessment, regardless of their level of interaction with animals and whether anything has changed since their last assessment. Once the OHS Assessment has been reviewed and accepted, the OHS staff will send a notification to the IACUC office regarding your status.

Please note that only the OHS staff may review health information, therefore please direct any questions, concerns or medical forms directly to the OHS staff for your campus. Any medical forms sent to the IACUC office will be deleted without review.

Mandatory Animal Care and Use (MACU) Training

The IACUC provides a standardized training program of institutional and regulatory requirements. This program, called the Mandatory Animal Care and Use (MACU) training, provides education on how to comply with animal regulations, institutional policies, and the guidelines and procedures within centralized animal facilities for each campus. Protocol personnel are required to complete this training prior to working with live animals and repeat the training every three years. In the interim, it can serve as a useful resource for many questions concerning the IACUC and review of animal research.

To receive credit for the training, you must view the presentation, review the institutional policies, and complete a quiz. The animal user will need to obtain at least an 80% (16 out of 20) on the quiz to pass. If an 80% score is not achieved, the IACUC office will arrange a make-up quiz.

Please contact the IACUC office if you have any questions concerning the material covered in the training.

Rodent Survival Surgery (RSS) Training

Personnel that will be conducting survival surgery on rodents must complete the RSS training as a part of their IACUC clearance and repeat the training every three years. This must be done prior to conducting survival surgery. The IACUC office must be notified of intent to conduct survival surgery by indicating on the Supplement P form or by email if the person is already listed on the protocol. The IACUC office will then contact the personnel with the training and quiz instructions. A grade of 70% or higher is required for credit of completion.

Tufts CMS, LAMS, and CBU offer additional training on rodent handling and surgical techniques. Please reach out to those groups for more information.

Access Requests

After IACUC clearance has been attained, information about getting an ID and/or access to the animal facilities can be requested be emailing All Boston campus access requests should include specific room numbers. If you do not have a Tufts University or Tufts Medical Center ID card, please notify the IACUC Office upon receiving IACUC clearance or when requesting animal facility access. The IACUC Office will initiate the process for a Tufts Affiliate ID. We will need to know the month and day of your birth to submit the form.

Frequently Asked Questions

I’ve already completed my training and/or OHS assessment, why am I being asked to complete this again?

Annual completion of the OHS assessment is required. Both MACU and RSS training must be repeated every 3 years. The IACUC office will begin sending renewal reminders well in advance of the expiration date. If an individual fails to renew OHS or mandatory training requirements, the IACUC office will remove the person from the animal protocol, revoke animal facility access, and inform the Principal Investigator that the person is not approved to work with animals.

How do I add someone to an IACUC protocol?

Addition of personnel to an active protocol can be done administratively through the use of a Supplement P. Email the completed form to the Click here for more information on personnel amendments.

Why can’t I send the IACUC office my OHS assessment?

The IACUC office cannot legally receive or transmit any OHS forms. Only the OHS staff may review health information. Please direct any questions, concerns, or medical forms directly to the OHS staff for your campus which can be found on the Materials webpage.

Can I get a head start on completing my IACUC clearance requirements, prior to being added onto a protocol?

Absolutely! Please email for more information on personnel requirements and instructions for accessing the Materials webpage. Principal Investigators are to share this information with any personnel who will be working on their IACUC protocols, prior to IACUC approval.

When can I request access to the animal facilities?

After you complete both the MACU and OHS assessment, you will receive an IACUC clearance notification. Once you receive this notification, you will be added to the appropriate IACUC protocol and are free to request access by emailing

Does the IACUC office offer supplemental trainings on technical procedures?

The animal health services group on each campus (DLAM, LAMS, and CBU) offers supplemental trainings on technical procedures. Please reach out to them directly for additional training.