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Each institution that utilizes regulated species and that receives federal funding for research must have in place an Institutional Animal Care and Use Committee (IACUC). This Committee is mandated through two different federal regulations in order to ensure institutional compliance. Each institution provides a “contract” with federal granting agencies that the institution will uphold the regulations that govern laboratory animal care and use. This agreement with the federal government is our Public Health Service Assurance document, approved by the Office of Laboratory Animal Welfare (OLAW), at the National Institutes of Health (NIH). This Assurance must be in place so that our institution can receive federal funding for animal research.

Our IACUC ensures compliance by monitoring animal care and use through different mechanisms:

  1. Review and approval of all research and procedures proposed through the use of protocols and amendments.
  2. Inspection of all animal facilities and laboratories where animal work occurs.
  3. Review and generation of institutional policies and guidelines.
  4. Reports to the federal agencies.

The IACUC is comprised of institutional scientists that use animals, veterinarians, non-scientists affiliated with Tufts/Tufts Medical Center and at least one non-affiliated member to represent community interests and concerns. The IACUC serves as a resource for investigators and research staff on the use of regulated species in research and training.